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Apoptosis
(Single Best Answer) Question 1: Programmed cell death is known as ?
A) Cytolysis
B) Apoptosis
C) Necrosis
D) Proptosis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: Ladder pattern of DNA electrophoresis in apoptosis is caused by the action of the following enzyme ?
A) Endonuclease
B) Transglutaminase
C) DNAse
D) Caspase
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: In-situ DNA nick end labeling can quantitate ?
A) Fraction of cells in apoptotic pathways
B) Fraction of cells in S phase
C) p53 gene product
D) bcr/abl gene
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: In apoptosis, Apaf-1 is activated by release of which of the following substances from the mitochondria ?
A) Bcl-2
B) Bax
C) Bcl-XL
D) Cytochrome C
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: CD-95 has a major role in ?
A) Apoptosis
B) Cell necrosis
C) Interferon activation
D) Proteolysis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: Apoptosis can occur by changes in hormone levels in the ovarian cycle. When there is no fertilization of the ovum, the endometrial cells die because ?
A) The involution of corpus luteum causes estradiol and progesterone levels to fall dramatically
B) LH levels rise after ovulation
C) Estradiol levels are not involved in the LH surge phenomenon
D) Estradiol inhibits the induction of the progesterone receptor in the endometrium
Answer (Select an option above to get the answer):
(Single Best Answer) Question 7: Mitochondria is involved in all of the following, except ?
A) ATP production
B) Apoptosis
C) Tricarboxylic acid cycle
D) Fatty acid biosynthesis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 8: Chemotherapeutic drugs can cause ?
A) Only necrosis
B) Only apoptosis
C) Both necrosis and apoptosis
D) Anoikis
Answer (Select an option above to get the answer):
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