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(Single Best Answer) Question 1: A one year old boy presented with hepatosplenomegaly and delayed milestones. The liver biopsy and bone marrow biopsy revealed presence of histiocytes with PAS-positive. Diastase-resistant material in the cytoplasm. Electron-microscopic examination of these histiocytes is most likely to reveal the presence of ?
A) Birbeck granules in the cytoplasm
B) Myelin figures in the cytoplasm
C) Parallel rays of tubular structures in lysosomes
D) Electron dense deposit in the mitochondria
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: A 2 year old child comes with discharge, seborrheic dermatitis, polyuria and hepatosplenomegaly. Which of the following is the most likely diagnosis ?
A) Leukemia
B) Lymphoma
C) Langerhan's cell histiocytosis
D) Germ cell tumor
Answer (Select an option above to get the answer):
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