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Maculopapular Rash
(Single Best Answer) Question 1: A four year old boy was admitted with a history of abdominal pain and fever for two months, maculopapular rash for ten days, and dry cough, dyspnea and wheezing for three days. On examination, liver and spleen were enlarged 4 cm and 3 cm respectively below the costal margins. His hemoglobin was 10.0 g/dl, platelet count 37 x 109/L and total leukocyte count 70 x 109/L, which included 80% eosinophils. Bone marrow examination revealed a cellular marrow comprising 45% blasts and 34% eosinophils and eosinophilic precursors. The blasts stained negative for myeloperoxidase and non-specific esterase¬ and were positive for CD 19, CD 10, CD22 and CD20. Which one of the following statements in not true about this disease ?
A) Eosinophils are not part of the neoplastic clone
B) t(5; 14) rearrangement may be detected in blasts
C) Peripheral blood eosinophilia may normalize with chemotherapy
D) Inv (16) is often detected in the blasts and the eosinophils
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: A man presents with fever and chills 2 weeks after a louse bite. There was a maculopapular rash on the trunk which spread peripherally. The cause of this infection can be ?
A) Scrub typhus
B) Endemic typhus
C) Rickettsial pox
D) Epidemic typhus
Answer (Select an option above to get the answer):
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