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Medical Oncology
(Single Best Answer) Question 1: The new agent pemetrexed, useful in breast cancer, belongs to which of the following category of drugs ?
A) Antitumor antibiotic
B) Alkylating agent
C) Hormonal agent
D) Antimetabolite
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: The treatment of choice for Anaplastic carcinoma of thyroid infiltrating trachea and sternum will be ?
A) Radical excision
B) Chemotherapy
C) Radiotherapy
D) Palliative / Symptomatic therapy
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: Which of the following is the most effective intravesical therapy for superficial bladder cancer ?
A) Mitomycin
B) Adriamycin
C) Thiotepa
D) BCG
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: Which of the following chemotherapeutic drugs has selective action on hypoxic tumor cells ?
A) Mitomycin C
B) Cisplatin
C) Doxorubicin
D) 5 Flurouracil
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: The chemotherapeutic agent, most commonly administered by continuous infusion, is ?
A) Ara-C
B) 5-FU
C) Cisplatin
D) Etoposide
Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: Which of the following statements is not true ?
A) Patiens with IgD myeloma may present with no evident M-spike on serum electrophoresis
B) A diagnosis of plasma cell leukemia can be made if circulating peripheral blood plasmablasts comprise 14% of peripheral blood white cells in a patient with white blood cell count of 11 X 100 /L and platelet count of 88 X 109 /L
C) In smoldering myeloma plasma cells constitute 10 - 30% of total bone marrow cellularity
D) In a patient with multiple myeloma, a monoclonal light chain may be detected in both serum and urine
Answer (Select an option above to get the answer):
(Single Best Answer) Question 7: Regarding testicular tumors, the following are false except ?
A) They are the commonest malignancy in older men
B) Seminomas are radiosensitive
C) Only 25% of Stage I teratomas are cured by surgery alone
D) Chemotherapy rarely produces a cure in those with metastatic disease
Answer (Select an option above to get the answer):
(Single Best Answer) Question 8: A 58 year old woman has been diagnosed with locally advanced breast cancer and has been recommended for chemotherapy. She has five years history of myocardial infarction and congestive heart failure. Which anti-neoplastic drug shoud be best avoided ?
A) Anthracycline
B) Alkylating agent
C) Platinum compound
D) Biphosphonates
Answer (Select an option above to get the answer):
(Single Best Answer) Question 9: Chemotherapeutic drugs can cause ?
A) Only necrosis
B) Only apoptosis
C) Both necrosis and apoptosis
D) Anoikis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 10: Which one of the following is not a feature of multiple myeloma ?
A) Hypercalcemia
B) Anemia
C) Hyperviscocity
D) Elevated alkaline phosphatase
Answer (Select an option above to get the answer):
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