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Multiple Myeloma
(Single Best Answer) Question 1: Which of the following situations will lead to increased viscosity of blood ?
A) Fasting state
B) Hypoglycemia
C) Multiple myeloma
D) Amyloidogenesis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: Splenomegaly is characteristic of which of the following conditions ?
A) Idiopathic thrombocytopenic purpura
B) Chronic myeloid leukemia
C) Hairy cell leukemia
D) Multiple myeloma
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: Which of the following statements is not true ?
A) Patiens with IgD myeloma may present with no evident M-spike on serum electrophoresis
B) A diagnosis of plasma cell leukemia can be made if circulating peripheral blood plasmablasts comprise 14% of peripheral blood white cells in a patient with white blood cell count of 11 X 100 /L and platelet count of 88 X 109 /L
C) In smoldering myeloma plasma cells constitute 10 - 30% of total bone marrow cellularity
D) In a patient with multiple myeloma, a monoclonal light chain may be detected in both serum and urine
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: A renal biopsy from a 56 years old women with progressive renal failure for the past 3 years shows glomerular and vascular deposition of pink amorphous material. It shows apple-green birefringence under polarized light after Congo red staining. These deposits are positive for lambda light chains. The person is most likely to suffer from ?
A) Rheumatoid arthritis
B) Tuberculosis
C) Systemic lupus erythematosus
D) Multiple myeloma
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: Tophus is the pathognomonic lesion of which of the following condition ?
A) Multiple myeloma
B) Cystinosis
C) Gout
D) Eale's disease
Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: A 50 year old man presented with orbital mass. Systemic examination revealed anaemia and investigations revealed hypergammaglobilinemia. The patient should be investigated to rule out ?
A) Squamous cell carcinoma
B) Optic nerve glioma
C) Multiple myeloma
D) Malignant melanoma
Answer (Select an option above to get the answer):
(Single Best Answer) Question 7: Which one of the following is not a feature of multiple myeloma ?
A) Hypercalcemia
B) Anemia
C) Hyperviscocity
D) Elevated alkaline phosphatase
Answer (Select an option above to get the answer):
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