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Pathology
(Single Best Answer) Question 1: The following diseases have autosomal dominant inheritance except ?
A) Polycystic kidney disease
B) Peutz Jegher syndrome
C) Phenylketonuria
D) Von Williebrand disease
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: CSF examination in a case of tubercular meningitis shows all of the following except ?
A) Elevated protein levels
B) Raised sugar level
C) low chloride level
D) Lymphocytosis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: The mode of inheritance of hereditary elliptocytosis is ?
A) Autosomal dominant
B) Autosomal recessive
C) X-linked recessive
D) X-linked dominant
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: CD 3 is a marker for ?
A) B Lymphocytes
B) T Lymphocytes
C) Macrophages
D) Activated B lymphocytes
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: A 7 year old boy presented with generalised oedema. Urine examinations revealed marked albuminuria. Serum biochemical examinations showed hypoalbuminemia with hyperlipidemia. Kidney biopsy was undertaken. On light microscopic examination, the kidney appeared normal. Electron microscopic examination is most likely to reveal ?
A) Fusion of foot processes of the glomerular epithelial cells
B) Rarefaction of glomerular basement membrane
C) Deposition of electron dense material in the basement membrane
D) Thin basement membrane
Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: A one year old boy presented with hepatosplenomegaly and delayed milestones. The liver biopsy and bone marrow biopsy revealed presence of histiocytes with PAS-positive. Diastase-resistant material in the cytoplasm. Electron-microscopic examination of these histiocytes is most likely to reveal the presence of ?
A) Birbeck granules in the cytoplasm
B) Myelin figures in the cytoplasm
C) Parallel rays of tubular structures in lysosomes
D) Electron dense deposit in the mitochondria
Answer (Select an option above to get the answer):
(Single Best Answer) Question 7: In which of the following conditions of malabsorption, an intestinal biopsy is diagnostic ?
A) Celiac disease
B) Tropical sprue
C) Whipple's disease
D) Lactose intolerance
Answer (Select an option above to get the answer):
(Single Best Answer) Question 8: Which of the following is the most likely inheritance pattern in the pedigree given below ?
                                        ■──┬──○
                   ┌──────┬──────────┬──────┬────┐
                   ●              □                       ●              ●          □
              ┌┬┴┐       ┌─┴─┐              ┌─┴┬──┬───┐
              ■ ●  □       □       ○              ■      □    ●       ○
A) Autosomal dominant
B) Mitochondrial
C) Autosomal recessive
D) X-linked dominant
Answer (Select an option above to get the answer):
(Single Best Answer) Question 9: If both husband and wife are suffering with achondroplasia, what are their chances of having a normal child ?
A) 0%
B) 25%
C) 50%
D) 100%
Answer (Select an option above to get the answer):
(Single Best Answer) Question 10: A patient has been injected with Penicillin Injection 48 hours ago. He has no prior history of allergy to Penicillin. He now develops wheeze and hemolysis and is positive for antibodies to Penicillin. Type of hypersensitivity is ?
A) Type I
B) Type II
C) Type III
D) Type IV
Answer (Select an option above to get the answer):
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