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Polyuria
(Single Best Answer) Question 1: A 6-month old boy weighing 3.2 kg presents with recurrent vomiting and polyuria. Investigations show blood urea 60 mg / dL, creatinine 0.7 mg / dL, calcium 12.8 mg / dL, phosphate 3 mg / dL, pH 7.45, bicarbonate 25 mEq/L and PTH 140 pg / ml (normal < 60 pg / ml). Daily urinary calcium excretion is reduced. Ultrasound abdomen show bilateral nephrocalcinosis. The most likely diagnosis is ?
A) Bartter syndrome
B) Mutation of the calcium sensing receptor
C) Pseudo-pseudohypoparathyroidism
D) Parathyroid adenoma
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: A 11-month old boy, weighing 3 kg, has polyuria, polydipsia and delayed motor milestones. Blood investigations show creatinine of 0.5 mg/dl, potassium 3mEq/L, sodium 125 mEq/L, chloride 88 mEq/L, calcium 8.8 mg/dl, pH 7.46 and bicarbonate 26 mEq/L. Ultrasonography shows medullary nephrocalcinosis. The most likely diagnosis is ?
A) Renal tubular acidosis
B) Diabetes insipidus
C) Bartters syndrome
D) Pseudohypoaldosteronism
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: A 10 month old boy, weighing 3 kg has polyuria, polydipsia and delayed motor milestones. Investigations show blood levels of creatinine 0.5 mg/dL. potassium 3 mEq/L, sodium 125 mEq/L, chloride 88 mEq/L, calcium 8.8 mg/dL, pH - 7.46, and bicarbonate 26 mEq/L. Ultrasonography shows medullary nephrocalcinosis. The most likely diagnosis is ?
A) Renal tubular acidosis
B) Diabetes insipidus
C) Bartter syndrome
D) Pseudohypoaldosteronism
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: A 55 year old man, a chronic smoker is brought to emergency with history of polyuria, polydipsia, nausea and altered sensorium for last two days. He had been diagnosed as having squamous cell carcinoma of lung two months prior to this. On examination, he was lethargic and confused. An ECG was normal except for a narrowed QT interval. Which one of the following is the most likely metabolic abnormality ?
A) Hypernatremia
B) Hypercalcemia
C) Hypokalemia
D) Hyponatremia
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: A 2 year old child comes with discharge, seborrheic dermatitis, polyuria and hepatosplenomegaly. Which of the following is the most likely diagnosis ?
A) Leukemia
B) Lymphoma
C) Langerhan's cell histiocytosis
D) Germ cell tumor
Answer (Select an option above to get the answer):
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