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Zidovudine
(Single Best Answer) Question 1: An HIV- positive patient is on anti-retroviral therapy with zidovudine, lamivudine and indinavir. He is proven to be suffering from genito-urinary tuberculosis. Which one of the following drugs should not be given to this patient ?
A) Isoniazid
B) Rifampicin
C) Pyrazinamide
D) Ethambutol
Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: All of the following strategies are effective in preventing mother to child transmission of HIV, except ?
A) Zidovudine to mother and baby
B) Vaginal cleansing before delivery
C) Stopping breast feeding
D) Elective caesarian section
Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: A resident doctor sustained a needlestick injury while sampling blood of a patient who is HIV positive. A decision is taken to offer him post-exposure prophylaxis. Which one of the following would be the best recommendation ?
A) Zidovudine + Lamivudine for 4 weeks
B) Zidovudine + Lamivudine + Nevirapine for 4 weeks
C) Zidovudine + Lamivudine + Indinavir for 4 weeks
D) Zidovudine + Stavudine + Nevirapine for 4 weeks
Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: Resistance to zidovudine develops due to ?
A) Mutations at reverse transcriptase
B) Increased efflux of the drug from inside the cell
C) Increased metabolism of the drug
D) Decreased zidovudine 5 triphosphate formation
Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: Which of following antiretroviral drugs is a non-nucleoside reverse transcriptase inhibitor ?
A) Zidovudine
B) Efavirenz
C) Saquinavir
D) Stavudine
Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: The antiretroviral drug implicated in the development of heart muscle disease ?
A) nevirapine
B) efavirenz
C) zidovudine
D) emtricitabine
Answer (Select an option above to get the answer):
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