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JIPMER >
2003 >
Microbiology
> Explanation
- Type II hypersensitivity reactions include all of
the following, except?
A. Arthus reaction
B. Good pasture's syndrome
C. Myasthenia gravis
D. Hemolytic anaemia
Ans: A) Arthus reaction
Explanation -
Type II Hypersensitivity reactions / Cytotoxic
reactions - mediated by antibodies directed towards
antigens present on the cell surfaces resulting in damage to
the cells.
The antibody produced may be IgM or IgG type
Note:
B) Good Pasture's syndrome - Antibody
against Glomerular basement membrane
C) Myasthenia gravis - Antibody against Acetylcholine
receptors
D) Hemolytic anaemia - Antibodies against red cell surface
antigens
Type III Hypersensitivity reactions / Immune complex
reactions - characterised by deposition of Antigen-
Antibody complexes in tissues, activation of complement and
infiltration of leukocytes (neutrophils) leading to tissue
damage
E.g. - Arthus reaction, Serum
Sickness
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