Question 1: A 59 year old man with severe myxomatous mitral regurgitation is asymptomatic, with a left ventricular ejection fraction of 45% and an end-systolic diamater index of 2.9 cm/m2. The most appropriate treatment is ?
A) Mitral valve repair of replacement
B) No treatment
C) ACE inhibitor therapy
D) Digoxin and diruretic therapy
Answer:
Question 2: Palpable purpura could occur in the following conditions, except ?
A) Thrombocytopenia
B) Small-vessel vasculitis
C) Disseminated gonococcal infection
D) Acute meningococcemia
Answer:
Question 3: A 30 years old male patient presents with complaints of weakness in right upper and both lower limbs for last 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5th finger on left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. Investigations showed a Hb-12gm, TLC-12000Cu mm, Platelets 4,30,000, ESR- 49 mm. Urine examination showed proteinuria and RBC 10 - 15 /hpf with no casts. Which of the following is the most likely diagnosis ?
A) Polyarteritis nodosa
B) Systemic lupus erythematosus
C) Wegener's granulomatosis
D) Mixed cryoglobulinemia
Answer:
Question 4: Which of the following infestation leads to malabsorption ?
A) Giardia lamblia
B) Ascaris lumbricoides
C) Necator americana
D) Ancyclostoma duodenale
Answer:
Question 5: All of the following can cause osteoporosis, except ?
A) Hyperparathyroidism
B) Steroid use
C) Fluorosis
D) Thyrotoxicosis
Answer:
Question 6: Serum angiotensin converting enzyme may be raised in all of the following except ?
A) Sarcoidosis
B) Silicosis
C) Berylliosis
D) Bronchogenic carcinoma
Answer:
Question 7: Hypercalcemia associated with malignancy is most often mediated by ?
A) Parathyroid hormone (PTH)
B) Parathyroid hormone related protein (PTHrP)
C) Interleukin - 6 (IL-6)
D) Calcitonin
Answer:
Question 8: All of the following are the causes of relative polycythemia except ?
A) Dehydration
B) Dengue haemorrhagic fever
C) Gaisbock syndrome
D) High altitude
Answer:
Question 9: All of the following may cause ST segment elevation on EKG, except ?
A) Early repolarization variant
B) Constrictive pericarditis
C) Ventricular aneurysm
D) Prinzmetal angina
Answer:
B
Question 10: 5' - Nucleotidase activity is increased by ?
A) Bone diseases
B) Prostate cancer
C) Chronic renal failure
D) Cholestatic disorders
Answer:
Question 11: Normal CSF glucose level in a normoglycemic adult is ?
A) 20 - 40 mg/dL
B) 40 - 70 mg/dL
C) 70 - 90 mg/dL
D) 90 - 110 mg/dL
Answer:
B
Question 12: Bart's hydrops fetalis is lethal because ?
A) Hb Bart's cannot bind oxygen
B) The excess α - globin form insoluble precipitates
C) Hb Bart's cannot release oxygen to fetal tissues
D) Microcytic red cells become trapped in the placenta
Answer:
C
Question 13: Cluster headache is characterized by all, except ?
A) Affects predominantly females
B) Unilateral headache
C) Onset typically in 20 - 50 years of life
D) Associated with conjunctival congestion
Answer:
A
Question 14: The most sensitive test for the diagnosis of myasthenia gravis is ?
A) Elevated serum Ach-receptor binding antibodies
B) Repetitive nerve stimulation test
C) Positive edrophonium test
D) Measurement of jitter by single fibre electromyography
Answer:
Question 15: Vitamin B12 deficiency can give rise to all of the following except ?
A) Myelopathy
B) Optic atrophy
C) Peripheral neuropathy
D) Myopathy
Answer:
Question 16: EEG is usually abnormal in all of the following except ?
A) Subacute sclerosing panencephalitis
B) Locked - in state
C) Creutzfeldt - Jackob disease
D) Hepatic encephalopathy
Answer:
Question 17: All of the following are neurologic channelopathies except ?
A) Hypokalemiac periodic paralysis
B) Episodic ataxia type I
C) Familial hemiplegic migraine
D) Spinocerebellar ataxia I
Answer:
Question 18: All of the following conditions are known to cause diabetes insipidus except ?
A) Multiple sclerosis
B) Head injury
C) Hsitiocytosis
D) Viral encehalitis
Answer:
A
Question 19: Antipsychotic drug-induced parkinsonism is treated by ?
A) Anticholinergics
B) Levodopa
C) Selegiline
D) Amantadine
Answer:
A
Question 20: Which one of the following is used in therapy of Toxoplasmosis ?
A) Artensenuate
B) Thiacetazone
C) Ciprofloxacin
D) Pyrimethamine
Answer:
D
Question 21: Which of the following drugs is useful in prophylaxis of migraine
A) Propranolol
B) Sumatriptan
C) Domperidone
D) Ergotamine
Answer:
A
Question 22: The most common pathogens responsible for nosocomial pneumonias in the ICU are ?
A) Gram positive organisms
B) Gram negative organisms
C) Mycoplasma
D) Virus infections
Answer:
Question 23: A 50 year old man, an alcoholic and a smoker presents with a 3 hour history of severe retrosternal chest pain and increasing shortness of breath. He started having this pain while eating, which was constant and radiated to the back and interscapular region. He was a known hypertensive. On examination, he was cold and clammy with a heart rate of 130/min, and a BP of 80/40 mm Hg. JVP was normal. All peripheral pulses were present and equal. Breath sounds were decreased at the left lung base and chest x-ray showed left pleural effusion. Which one of the following is the most likely diagnosis ?
A) Acute aortic dissection
B) Acute myocardial infarction
C) Rupture of the esophagus
D) Acute pulmonary embolism
Answer:
A
Question 24: Which of the following is a cause of reversible dementia ?