Question 1: With reference to infections with Escherichia coli the following are true except ?
A) Enteroaggregative E.coli is associated with Persistent diarrhoea
B) Enterohemorrhagic E.coli can cause haemolytic uraemic syndrome
C) Enteroinvasive E.coli produces a disease similar to salmonellosis
D) Enterotoxigenic E.coli is a common cause of traveler's diarrhoea
Answer:
Question 2: The following statements are true regarding melioidosis except ?
A) It is caused by Burkholderia mallei
B) The agent is a gram negative aerobic bacteria
C) Bipolar staining of the aetiological agent is seen with methylene blue stain
D) The most common form of melioidosis is pulmonary infection
Answer:
Question 3: The following bacteria are most often associated with acute neonatal meningitis except ?
A) Escherichia coli
B) Streptococcus agalactiae
C) Neisseria meningitidis
D) Listeria monocytogenes
Answer:
Question 4: All of the following Vibrio sp. are halophilic, except ?
A) V.cholerae
B) V.parahaemolyticus
C) V.alginolyticus
D) V.fluvialis
Answer:
A
Question 5: All of the following organisms are known to survive intracellularly except ?
A) Neisseria meningitides
B) Salmonella typhi
C) Streptococcus pyogenes
D) Legionella pneumophila
Answer:
Question 6: The capsule of Cryptococcus neoformans in a CSF sample is best seen by ?
A) Grams stain
B) India ink preparation
C) Giemsa stain
D) Methanamine - Silver stain
Answer:
Question 7: Viruses can be isolated from clinical samples by cultivation in the following except ?
A) Tissue culture
B) Embryonated eggs
C) Animals
D) Chemically defined media
Answer:
Question 8: It is true regading the normal microbial flora present on the skin and mucous membranes that ?
A) It cannot be eradicated by antimicrobial agents
B) It is absent in the stomach due to the acidic pH
C) It establishes in the body only after the neonatal period
D) The flora in the small bronchi is similar to that of the trachea
Answer:
B
Question 9: An army jawan posted in a remote forest area had fever and headache. His fever was 104°F and pulse was 70 per min. He had an erythematous lesion of about 1 cm on the leg surrounded by small vesicles, along with generalized lymphadenopathy at the time of presentation to the referral hospital. His blood sample was collected to perform serology for the diagnosis of Rickettsial disease. Which one of the following results in Weil-felix reaction will be diagnostic in this clinical setting ?
A) High OX-2
B) High OX-19
C) High OX-K
D) High OX-19 and OX-2
Answer:
Question 10: Adenosine deaminase (enzyme) deficiency is associated with ?
A) Severe combined immunodeficiency (SCID)
B) X-linked agammaglobulinemia
C) Transient hypogammaglobulinemia of infancy
D) Chronic granulomatous disease
Answer:
A
Question 11: Which of the following viral infections is transmitted by tick ?
A) Japanese encephalitis
B) Dengue fever
C) Kyasanur forest disease (KFD)
D) Yellow fever
Answer:
Question 12: Atypical pneumonia can be caused by the following microbial agents except ?
A) Mycoplasma pneumoniae
B) Legionella pneumophila
C) Human Corona virus
D) Klebsiella pneumoniae
Answer:
Question 13: The serum concentration of which of the following human IgG subclass is maximum ?
A) IgG1
B) IgG2
C) IgG3
D) IgG4
Answer:
A
Question 14: Chalamydia trachomatis is associated with the following except ?
A) Endemic trachoma
B) Inclusion conjunctivitis
C) Lymphogranuloma venereum
D) Community acquried pneumonia
Answer:
D
Question 15: The following statements are true regarding Clostridium perfringens except ?
A) It is the commonest cause of gas gangrene
B) It is normally present in human faeces
C) The principal toxin of C.perfringens is the alpha toxin
D) Gas gangrene producing strains of C.perfringens produce heat resistant spores
Answer:
Question 16: The most common organism amongst the following that causes acute meningitis in an AIDS patient is ?
A) Stretococus pneumoniae
B) Streptococcus agalactiae
C) Cryptococcus neoformans
D) Listeria monocytogenes
Answer:
Question 17: A bacterial disease that has been associated with the 3 "Rs" i.e., rats, ricefields, and rainfall is ?
A) Leptospirosis
B) Plague
C) Melioidosis
D) Rodent-bite fever
Answer:
A
Question 18: A child was diagnosed to be suffering from diarrhoea due to Camplyobacter jejuni. Which of the following will be the correct enviornmental conditions of incubation of the culture plates of the stool sample ?
A) Temperature of 42°C and microaerophilic
B) Temperature of 42°C and 10% carbondioxide
C) Temperature of 37°C and microaerophilic
D) Temperature of 37°C and 10% carbondioxide
Answer:
Question 19: Which one of the following statements is true regarding Chlamydia pneumoniae ?
A) Fifteen serovars have been identified as human pathogens
B) Mode of transmission is by the airborne bird excreta
C) The cytoplasmic inclusions present in the sputum specimen are rich in glycogen
D) The group specific antigen is responsible for the production of complement fixing antibodies
Answer:
Question 20: Which of the following is not a neuroparasite ?
A) Taenia solium
B) Acanthamoeba
C) Naegleria
D) Trichinella spiralis
Answer:
D
Question 21: Virus mediated transfer of host DNA from one cell to another is known as ?
A) Transduction
B) Transformation
C) Transcription
D) Integration
Answer:
A
Question 22: HIV can be detected and confirmed by ?
A) Polymerase Chain Reaction (PCR)
B) Reverse Transcriptase - PCR
C) Real Time PCR
D) Mimic PCR
Answer:
B
Question 23: In the small intestine, cholera toxin acts by ?