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2003 June > Microbiology
- The immunoglobin that can be transferred to the
foetus transplacentally is?
A. IgA
B. IgG
C. IgM
D. IgE
E. IgD
Ans: B
[Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
Immunoglobulins
The minimum (further minimized)
| |
IgG |
IgA |
IgM |
IgD |
IgE |
| Property |
|
|
|
|
|
| Placental
crossing |
yes |
no |
no
|
no |
no |
| Milk |
present |
present |
no |
no
|
no |
| |
|
|
|
|
|
| Complement
fixing |
Classical
pathway |
Alternative
pathway |
Classical
pathway |
no |
no |
| |
|
('A' for
'Alternative') |
|
|
|
| |
|
|
|
|
|
|
Half life |
23
days (longest) |
6
days |
5
days |
2.8
days |
2.3
days(shortest) |
| Serum conc
(mg%) |
maximum |
|
|
|
minimum |
| |
|
|
|
|
|
| Valency |
2
(monomer) |
2 or
its multiple
(di or trimer) |
10
(pentamer) |
2
(monomer) |
2
(monomer) |
|
So, B is the answer]
- The immunoglobulin activating classical complement
pathway is?
A. IgG
B. IgD
C. IgA
D. IgM
E. IgE
Ans: A, D
[Correction by "Tom" via email,
thanks...!!!][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
Referring back to the table of Question No. 1 -
We see that A & D are the answers]
- Epstein Barr virus is implicated in causation of ?
A. Burkitt's lymphoma
B. Hogkin's lymphoma
C. Nasopharyngeal carcinoma
D. Renal cell carcinoma
E. Hepatocellular carcinoma
Ans: A, B, C
[Ref: Harrisons's 15th][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
EBV - is associated with -
- Infectious mononucleosis - it is the causative agent
of this condition
- Burkitt's lymphoma
- Nasopharyngeal carcinoma
- Hodgkin's disease
- B cell lymphoma - in immunodeficient pts (such as
AIDS)]
- Among the following microorganisms, the ones that
posses a capsule are?
A. Cryptococci
B. Candida albicans
C. Haemophilus influenzae
D. Histoplasma capsulatum
Ans: A, C
[Ref: Paniker & Harrison's 15th][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
Capsule is found in -
| Nature of capsule |
Organism |
| |
|
| Polysaccharide |
Streptococus pneumoniae
Klebsiella
Enterobacter
Cryptococcus |
| |
|
| Polypeptide |
B. anthracis |
| |
|
| Hyaluronic acid |
Streptococcus pyogenes |
| |
|
| Others |
N. meningitidis
H. influenzae
Clostridium welchii |
|
Despite its name H.
capsulatum is uncapsulated
Candida is also not capsulated.
So, A, C are the answers]
- The causative agent(s) of pseudomembranous colitis
include?
A. Staphylococci
B. Streptococci
C. Pseudomonas
D. Clostridium difficile
E. Candida albicans
Ans: D
[Ref: P. Chakraborty, 1st, Pg-262][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation - Clostridium difficile and its toxin has
been found in feces of pts with acute pseudomembranous
colitis]
- In a precipitation reaction, prozone formation ?
A. is due to excess antigens
B. is due to excess antibodies
C. is due to broken antibodies
D. leads to false negative reaction
E. leads to false positive reaction
Ans: B
[Ref: P.Charkraborty, Pg-108][Corrected
by "Tom" via email, thanks...!!!][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
Prozone formation -
In antibody excess, all the available binding sites of
the antigens are taken up and a portion of the antibody
remains uncombined]
- True statment(s) about babesiosis include?
A. It is caused by Babesia microti
B. Causes bone marrow suppression
C. The organism is found within RBC's
D. The organism is found within WBC's
E. Chloroquine is used in its treatment
Ans: A, C,
[Ref: Harrison's 15th,
Chapter214][Solution by "Tom" via email, thanks....!!!]
[Explanation -
Babesiosis -
- Causative organism of is -
Babesia microti
- Transmission is by - Ticks (Ixodes
scapularis, I. ricinus are
main vectors)
- The organism
enters the RBCs and
resembles malarial parasites morpholoigcally
- Treatment -
- Is adviced for all pts
infected with babesia
- Combination of Quinine sulfate
(650mg salt orally tid) +
Clindamycin (600mg orally tid / 1.2 g
parenterally bid) for 7 - 10 days in adults
- Atovaquone + Azithromycin
may be effective when above
fails
- Exchange transfusion
may be required in asplenic pts
with high levels of parasitemia]
- True about cerebral malaria include?
A. Most commonly caused by P.vivax
B. Pathogenesis involves ischemia following capillary
blockage
C. There is hyperviscosity of blood
D. There is hyperglycemia
E. Signs of meningitis may be absent
Ans: B, C, E
[Solution by "Tom" via email,
thanks...!!!][Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
[Explanation -
A. Cerebral malaria - is a characterstic and ominous
feature of falciparum malaria.
So, this is false
B. True
C. True
D. Hypoglycemia is a common complication of severe
cerebral malaria - due to failure of hepatic
gluconeogenesis and increased consumption of glucose
So, this is false
E. There may be some passive resistance to flexion of
head, but signs of meningitis are characterstically
absent
So, this is true]
- True statement about Typhoid is/are ?
A. The bacteria are transported in water
B. Subclinical cases are rare
C. Chronic carrier state is common
D. Widal test is positive in the 1st week
E. Ty21a is an oral vaccine
Ans: C, E
[Contribute questions, options, answers,
explanations, to
mcqs@netmedicos.com ]
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