Home >> Medicine >> ForumTopic: Pulmonary Fibrosis
You need to be logged in to post messages.
| Author: | Message |
| superbdoc Total Posts: 273 | Posted: Thu Oct 16, 2008 09:02 pm Which one of the following is not likely to be associated with pulmonary fibrosis ? A) Coal miner's lung B) Primary sclerosing cholangitis C) Primary biliary cirrhosis D) Ankylosing spondylitis I was confused with B and C and so went wrong...plz your views...  |
| superbdoc Total Posts: 273 | Posted: Fri Oct 17, 2008 04:29 am Any takers..??  |
| superbdoc Total Posts: 273 | Posted: Sat Oct 18, 2008 06:33 pm ok...I will compile data later... |
| superbdoc Total Posts: 273 | Posted: Thu Oct 23, 2008 05:53 pm The final product of purine metabolism in non-primate mammals is ? A) Allantoin B) Ionosine C) Xanthine D) Uric acid I thought it was Allantoin only to b told by key as Xanthine...cud u pls clarify.. |
| superbdoc Total Posts: 273 | Posted: Thu Nov 06, 2008 07:25 pm Peripheral eosinophilia is not a characteristic feature of ? A) Hypersensitivity B) Allergic aspergillosis C) Tropical eosinophilia D) Loeffler's syndrome |
| superbdoc Total Posts: 273 | Posted: Fri Nov 07, 2008 03:40 pm Lung fibrosis It is important in the exam to be able to differentiate between conditions causing predominately upper or lower zone fibrosis. Fibrosis predominately affecting the upper zones • extrinsic allergic alveolitis • coal worker's pneumoconiosis/progressive massive fibrosis • silicosis • sarcoidosis • ankylosing spondylitis (rare) • histiocytosis • tuberculosis Fibrosis predominately affecting the lower zones • cryptogenic fibrosing alveolitis • most connective tissue disorders (except ankylosing spondylitis) • drug-induced: amiodarone, bleomycin, methotrexate • asbestosis |
Total Posts: 7 | Posted: Sat Nov 08, 2008 09:39 pm A & D are obvious exclusions as they are known causes of upper lobe fibrosis. Primary biliary cirrhosis is known to cause diffuse intersitial lung disease even to the extend of being granulomatous.PBC is also known to coexist with Sjogrens and Sarcoidosis,both of which are known to cause pulmonary fibrosis. Therefore the answer is B. Here is a small tip. Primary sclerosing cholangitis has an 87% association with ulcerative colitis and UC is treated with sulfasalazine,which is known to cause pulmonary infiltrates and fibrosis.So UC on treatment and not PSC causes fibrosis. Reference - Baum's Textbook of pulmonary diseases 5th edt. |
Total Posts: 7 | Posted: Sat Nov 08, 2008 10:13 pm Ans A. All the options except A)Hypersensitivity are known causes for peripheral eosinophilia. Check the Table 249-2 in 17th edt Harrison Pulmonary Infiltrates with Eosinophilia Etiology Known Allergic bronchopulmonary mycoses Parasitic infestations Drug reactions Eosinophilia-myalgia syndrome Idiopathic Causes Loeffler's syndrome Acute eosinophilic pneumonia Chronic eosinophilic pneumonia Allergic granulomatosis of Churg and Strauss Hypereosinophilic syndrome |