Home >> Study >> ForumTopic: Immunoglobulin FAQs
You need to be logged in to post messages.
| Author: | Message |
| superbdoc Total Posts: 273 | Posted: Wed Oct 08, 2008 12:59 am Max. concentration of IgG is in Parietal peritoneum (AIIMS Dec 94) Please add more facts into the thread...lets make an attempt... |
| jemzcal Total Posts: 127 | Posted: Wed Oct 08, 2008 07:59 am Ig with max concentration Ig G ( G1) |
| jemzcal Total Posts: 127 | Posted: Wed Oct 08, 2008 08:00 am Ig with maximum mass Ig M Ig with minimum mass Ig E |
| superbdoc Total Posts: 273 | Posted: Wed Oct 08, 2008 02:10 pm Ig with longest half life: Ig G Ig with shortest half life: Ig E |
| superbdoc Total Posts: 273 | Posted: Wed Oct 08, 2008 02:13 pm Facts abt IgE Heat-labile,Mediates Prausnitz kustner reaction,exhibits homocytotropism |
| jemzcal Total Posts: 127 | Posted: Wed Oct 08, 2008 08:08 pm Ig G transfer across placenta fixes compliment opsonisation |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:41 am Earliest immunoglobulin to be synthesised by foetus IgM |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:45 am IgA two types Serum IgA Valency 2 Secretory IgA Valency 4 |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:47 am IgM Effective valency is 5 even though theoretically 10 are possible |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:49 am Carbohydrate % is max in IgE |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:50 am Anti ABO is IgM Anti Rh is IgG |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 06:56 am Blocking antibodies are of IgG type .They create problems during serological diagnosis of Brucella |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 07:00 am Heavy chain 50000 Light chain 25000 Naming is based in heavy chain Antigen binds with hypervariable region .Site on hypervariable region making actual contact with epitop is known as CDR |
| Varunrag Total Posts: 72 | Posted: Thu Oct 09, 2008 07:06 am IgD has similar structure to IgG IgE is mostly extravascular |
| superbdoc Total Posts: 273 | Posted: Fri Oct 10, 2008 03:13 am Rheumatoid factor belongs to Ig M ( antibody against Fc fragment of Ig G ) Ig G1 and Ig M fix complements via classical pathway. Ig A,Ig D,Ig G4 fix complements via alternate pathway. |
| Varunrag Total Posts: 72 | Posted: Tue Oct 21, 2008 09:26 pm Heavy chain : chromosome 14 kappa chain 2 lambda chain 22 |
| varuchinu Total Posts: 44 | Posted: Wed Oct 22, 2008 02:59 am Ig D -- Dont fix complement. Ig A -- decreased in kwashiorkor |
| varuchinu Total Posts: 44 | Posted: Wed Oct 22, 2008 03:02 am Ig E decreased in Ataxia telengectasia. |
| docvijay Total Posts: 4 | Posted: Wed Oct 22, 2008 03:47 am commonest igG with max individual variation is igG2 |
| docvijay Total Posts: 4 | Posted: Wed Oct 22, 2008 03:48 am more specific anti rh belong to IgG 1 |
| docvijay Total Posts: 4 | Posted: Wed Oct 22, 2008 04:04 am conc of ig E in SERUM 0.004mg/dl wiscott aldrich syn igM-low igA AND igG -elevated or normal opsonisation mainly by igM |
| jemzcal Total Posts: 127 | Posted: Wed Oct 22, 2008 09:41 pm doc vijay, could you confirm on the last entry. as far as i know opsonisation is a function of IgG. we dont want people to be in the dark do we? |
| poulomi Total Posts: 15 | Posted: Thu Oct 23, 2008 12:47 pm hey jemscal, Ig with minimum mass is IgE or IgG??? cud u pls provide me the reference..... |
| jemzcal Total Posts: 127 | Posted: Thu Oct 23, 2008 03:17 pm hey poulomi, Ig with min mass- IgG(154kdaltons) IG with min conc- IgE(190kdaltons) referance Illustrated dictionary of Immunology by Julius M Cruise page 318. |
| jemzcal Total Posts: 127 | Posted: Thu Oct 23, 2008 03:46 pm its also wonderfully given in tabular form in harrisson17th table no308-11 |
| jemzcal Total Posts: 127 | Posted: Thu Oct 23, 2008 05:05 pm thanks for pointing it out poulomi. correction acknowledged  |
| docvijay Total Posts: 4 | Posted: Fri Oct 24, 2008 12:50 am hey jemzcal Ig G - NEUTRALISATION AND PRECIPITATION IgM - OPSONISATION REF ANANTNARAYAN CH- Ab n ig s..pg 84 clearly states ig M 500 - 1000 TIMES MORE effective in opsonisation than ig G |
| jemzcal Total Posts: 127 | Posted: Fri Oct 24, 2008 02:46 am thanks docvijay its just that i have this thought lingering still that opsonization is with IgG. I know AN specifies as you pointed out. does any1 have anything to add on? |
| jemzcal Total Posts: 127 | Posted: Sat Oct 25, 2008 02:08 am Hey there superbdoc. AIIMS ashish gupta dec94 has the question that u mentioned inmy book as IgG is maximum in a stomach b visceral peritonium c small intestine d large intestine and he doesnt give the answer. are we reading different books? what is the ruth regarding the answer of this q?\ is it parietal as you said?  |
| superbdoc Total Posts: 273 | Posted: Sat Oct 25, 2008 04:36 am Ya It seems the answer....I saw that answered in Rachna Chaurasiya Microbiology and this book has credibility at least thats whats those senior in this business tell me... |
| jemzcal Total Posts: 127 | Posted: Sat Oct 25, 2008 05:25 am ok buddy. thanks i guess we have lot of other things to cover rather than going after this one. the q in ashish gupta doesnt have the choice of parietl epithelium. |
| superbdoc Total Posts: 273 | Posted: Thu Jan 15, 2009 05:30 pm Any more do keep posting...  |
| jibbu Total Posts: 1 | Posted: Mon Feb 02, 2009 05:33 pm IgG appears first,for how much time it stays |
| superbdoc Total Posts: 273 | Posted: Mon Feb 02, 2009 09:14 pm What is sedimentation coefficient of all Igs..?? |