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| juhidr Total Posts: 149 | Posted: Tue Oct 21, 2008 06:24 am Immunotoxin Immunotoxins are made by attaching Monoclonal Antibodies to bacterial toxins such as diphtheria toxin or pseudomonal exotoxin (PE40), or to plant toxins such as ricin A or saporin. Immunotoxins have shown some early promise in shrinking lymphomas. The only immunotoxin approved for treating cancer is gemtuzumab ozogamicin. It has a toxin called calicheamicin, attached to an antibody against the CD33 antigen, which is present on most leukemia cells. Gemtuzumab is used to treat some people with acute myelogenous leukemia (AML). Another immunotoxin, BL22, showed promising results in early studies against some forms of chronic leukemia, even in patients who no longer responded to chemotherapy. A newer, improved version of this immunotoxin, known as HA22 (CAT-8015), is now being studied. |
| jemzcal Total Posts: 127 | Posted: Tue Oct 21, 2008 03:33 pm another example id DINELEUKIN DIFTITOX |
| superbdoc Total Posts: 273 | Posted: Thu Jan 15, 2009 05:30 pm brilliant!!  |