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Mcqs MBBS Exams India
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(Single Best Answer) Question 51: Diagnostic criteria of multiple myeloma includes which of the following ?
1. Increased malignant plasma cells in the bone marrow
2. Serum and/or urinary M protein
3. Skeletal lytic lesions
4. Skeletal blastic lesions

Select the correct answer using the code given below:
A) 1, 2 and 3
B) 1, 3 and 4
C) 1, 2 and 4
D) 2, 3 and 4
Answer (Select an option above to get the answer):
(Single Best Answer) Question 52: Which one of the following is NOT true regarding Chronic Myeloid Leukaemia (CML) ?
A) It is a clonal malignancy of haematopoetic stem
B) Risk of developing CML is increased in monozygotic twins
C) CMLS is defined by presence of BCR-ABL 1 fusion gene
D) 10 year survival with TKI therapy is 85%
Answer (Select an option above to get the answer):
(Single Best Answer) Question 53: Every individual carries four alpha gene alleles. Deletion of three alleles leads to development of ?
A) Haemoglobin X disease
B) Haemoglobin H disease
C) Haemoglobin F disease
D) Hydrops fetalis
Answer (Select an option above to get the answer):
(Single Best Answer) Question 54: Fever with splenomegaly and lymphadenopathy can be seen in ?
A) Infectious mononucleosis
B) Chronic leukaemia
C) Both infectious mononucleosis and chronic leukaemia
D) Neither infectious mononucleosis nor chornic leukaeia
Answer (Select an option above to get the answer):
(Single Best Answer) Question 55: Sickle cell disease may be associated with any of the following EXCEPT ?
A) Acute chest syndrome
B) Aplastic crisis
C) Splenic sequestration crisis
D) Conn's syndrome
Answer (Select an option above to get the answer):
(Single Best Answer) Question 56: Pyruvate kinase deficiency results in deficiency of ATP production and a chronic haemolytic anaemia. The disorder is inherited as an ?
A) Autosomal recessive trait
B) X-linked recessive trait
C) Autosomal dominant trait
D) X-linked dominant trait
Answer (Select an option above to get the answer):
(Single Best Answer) Question 57: Cryoprecipitate cannot be used for treatment of which one of the following conditions ?
A) Von Willebrand disease
B) Hypofibrinogenemia
C) Hemophilia - B
D) Hemophilia - A
Answer (Select an option above to get the answer):
(Single Best Answer) Question 58: All of the following are causes of reactive thrombocytosis, EXCEPT ?
A) Hemolytic anemia
B) Megaloblastic anemia
C) Post splenectomy
D) Chronic inflammatory disorders
Answer (Select an option above to get the answer):
(Single Best Answer) Question 59: Which one of the following investigations is NOT appropriate in a case of recurrent thrombosis ?
A) Antiphospholipid antibodies
B) Bcr-Abl assay
C) Protein C and S assays
D) Antithrombin level
Answer (Select an option above to get the answer):
(Single Best Answer) Question 60: A 35 year old man presents with history of low grade fever and headache for last five weeks. Clinical examination is remarkable for signs of meningismus. He undergoes lumbar puncture (LP) and a day later reports worsening of headache. Which one of the following features is NOT consistent with diagnosis of 'Post-LP' headache ?
A) Post-LP headache usually begins within 48 hours
B) Post-LP headache worsens in sitting position
C) Post-LP headache is most severe upon waking up
D) Post-LP headache may improve with caffeine intake
Answer (Select an option above to get the answer):