(Single Best Answer) Question 1: An 18 year old boy presents with digital gangrene in third and fourth fingers for last 2 weeks. On examination the blood pressure is 170/110 mm Hg and all peripheral pulses were palpable. Blood and urine examinations were unremarkable. Antinuclear antibodies, antibody to double stranded DNA and antineutrophil cytoplasmic antibody were negative. The most likely diagnosis is?
A) Wegener's granulomatosis B) Polyarteritis nodosa C) Takayasu's arteritis D) Systemic lupus erythematosus (SLE) Answer (Select an option above to get the answer):
(Single Best Answer) Question 2: A newly posted junior doctor had difficulty in finding out base deficit/ access for blood in given patient. An experienced senior resident gave him advise to find out quick method to determine acid-base composition of blood based on PCO2. Which of the following method he suggested to predict acid-base composition of blood?
A) Ref ford nomogram B) DuBio's nomogram C) Goldman constant field equation D) Siggard- Andersen nomogram Answer (Select an option above to get the answer):
(Single Best Answer) Question 3: A middle aged woman, on oral contraceptive for many years, developed neurological symptoms such as depression, irritability, nervousness and mental confusion. Her hemoglobin level was 8 g/dL. Biochemical investigations revealed that she was excreting highly elevated concentrations of xanthurenic acid in urine. She also showed high levels of triglycerides and cholesterol in serum. All the above findings are most probably related to vitamin B6 deficiency caused by prolonged oral contraceptive use except?
A) Increased urinary xanthurenic acid excretion B) Neurological symptoms by decreased synthesis of biogenic amines C) Decreased hemoglobin level D) Increased triglyceride and cholesterol level Answer (Select an option above to get the answer):
(Single Best Answer) Question 4: A 45 - year old woman visited her physician with complaints of increased appetite and thirst with increased frequency of urination. She also had the symptoms of diminished or impalpable pulses in the feet, besides gangrene of the feet. Her laboratory findings on the oral glucose tolerance test are as follows:
Parameters
Fasting
1 hr
2 hr
Blood glucose (mg/dL)
155
270
205
Urine glucose
-ve
+++
++
Ketone bodies
-ve
-ve
-ve
Which of the following statements is not correct for the above mentioned case ?
A) She was suffering from insulin dependent diabetes mellitus B) She was suffering from non-insulin dependent diabetes mellitus C) She was treated with oral hypoglycemic drugs only when diet control and exercise could not control the pathological situation D) Knowledge of family history of diabetes mellitus is useful in predicting the nature of diabetes Answer (Select an option above to get the answer):
(Single Best Answer) Question 5: A 20 year old woman presents with bilateral conductive deafness, palpable purpura on the legs and hemoptysis. Radiograph of the chest shows a thin-walled cavity in left lower zone. Investigations reveal total leukocyte count 12000/mm3, red cell casts in the urine and 12000/mm3 serum creatinine 3 mg/dL. What is the most probable diagnosis?
A) Henoch-Schonlein purpura B) Polyarteritis nodosa C) Wegener's granulomatosis D) Disseminated tuberculosis Answer (Select an option above to get the answer):
(Single Best Answer) Question 6: A woman is admitted with complaints of low-grade fever of 6 weeks duration. Chest radiograph reveals bihilar adenopathy with clear lung fields. All of the following investigations will be useful in differential diagnosis except?
A) CD4/CD8 counts in the blood B) Serum ACE levels C) CECT of chest D) Gallium scan Answer (Select an option above to get the answer):
A) Loss of diurnal variation B) Increased ACTH C) Increased plasma Cortisol D) Increased urinary metabolites of Cortisol Answer (Select an option above to get the answer):
(Single Best Answer) Question 8: The occurence of hyperthyroidism following administration of supplemental iodine to subjects with endemic iodine deficiency goitre is known as?
A) Jod- Basedow effect B) Wolff- Chaikoff effect C) Thyrotoxicosis factitia D) de Quervain's thyroiditis Answer (Select an option above to get the answer):
A) Chronic sinopulmonary disease B) Decreased level of alfa fetoprotein C) Chromosomal breakage D) IgA deficiency Answer (Select an option above to get the answer):